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Proteine und Peptide

ALCAM Recombinant Protein

Produktgrößen
10ug
£203,00
OPCD01240-10UG
50ug
£348,00
OPCD01240-50UG
200ug
£597,00
OPCD01240-200UG
Über dieses Produkt
SKU:
OPCD01240
Zusätzliche Namen:
Activated leukocyte cell adhesion molecule;CD166;CD166 antigen;MEMD.
Konjugat:
Unconjugated
Konzentration:
200 ug/mL (prior to lyoph)
Weitere Details:
Cell adhesion molecule that mediates both heterotypic cell-cell contacts via its interaction with CD6; as well as homotypic cell-cell contacts (PubMed:7760007; PubMed:15496415; PubMed:15048703; PubMed:16352806; PubMed:23169771; PubMed:24945728). Promotes T-cell activation and proliferation via its interactions with CD6 (PubMed:15048703; PubMed:16352806; PubMed:24945728). Contributes to the formation and maturation of the immunological synapse via its interactions with CD6 (PubMed:15294938; PubMed:16352806). Mediates homotypic interactions with cells that express ALCAM (PubMed:15496415; PubMed:16352806). Required for normal hematopoietic stem cell engraftment in the bone marrow (PubMed:24740813). Mediates attachment of dendritic cells onto endothelial cells via homotypic interaction (PubMed:23169771). Inhibits endothelial cell migration and promotes endothelial tube formation via homotypic interactions (PubMed:15496415; PubMed:23169771). Required for normal organization of the lymph vessel network. Required for normal hematopoietic stem cell engraftment in the bone marrow. Plays a role in hematopoiesis; required for normal numbers of hematopoietic stem cells in bone marrow. Promotes in vitro osteoblast proliferation and differentiation (By similarity). Promotes neurite extension; axon growth and axon guidance; axons grow preferentially on surfaces that contain ALCAM. Mediates outgrowth and pathfinding for retinal ganglion cell axons (By similarity).
Gendetails:
activated leukocyte cell adhesion molecule
Host:
E. coli
Molekulargewicht:
60kDa
Proteindetails:
CD166 antigen
Reinheit:
> 95%
Versandbedingungen:
Blue Ice
Quelle:
E.coli
Lagerbedingungen:
2Â[o]C to 8Â[o]C|-80Â[o]C
Hersteller:
Aviva Systems Biology
Typ:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins