AIM2 Recombinant Protein
Produktgrößen
10ug
£268,00
OPCD01224-10UG
50ug
£511,00
OPCD01224-50UG
200ug
£918,00
OPCD01224-200UG
Über dieses Produkt
- SKU:
- OPCD01224
- Zusätzliche Namen:
- Absent in melanoma 2;interferon-inducible protein AIM2;PYHIN4.
- Konjugat:
- Unconjugated
- Konzentration:
- 200 ug/mL (prior to lyoph)
- Weitere Details:
- Involved in innate immune response by recognizing cytosolic double-stranded DNA and inducing caspase-1-activating inflammasome formation in macrophages. Upon binding to DNA is thought to undergo oligomerization and to associate with PYCARD initiating the recruitment of caspase-1 precusrsor and processing of interleukin-1 beta and interleukin-18. Detects cytosolic dsDNA of viral and bacterial origin in a non-sequence-specific manner. Can also trigger PYCARD-dependent; caspase-1-independent cell death that involves caspase-8 (By similarity). Tumor suppressor which may act by repressing NF-kappa-B transcriptional activity.
- Gendetails:
- absent in melanoma 2
- Molekulargewicht:
- 44kDa
- Proteindetails:
- Interferon-inducible protein AIM2
- Reinheit:
- > 97%
- Versandbedingungen:
- Blue Ice
- Quelle:
- E.coli
- Lagerbedingungen:
- 2Â[o]C to 8Â[o]C|-80Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Datenblatt des Herstellers:html_datasheet.php