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Proteine und Peptide

ADAM17 Recombinant Protein

Produktgrößen
10ug
£279,00
OPCD01082-10UG
50ug
£543,00
OPCD01082-50UG
200ug
£994,00
OPCD01082-200UG
Über dieses Produkt
SKU:
OPCD01082
Zusätzliche Namen:
a disintegrin and metallopeptidase domain 17;a disintegrin and metalloprotease domain 17;a disintegrin and metalloproteinase domain 17 (tumor necrosis factor; alpha; converting enzyme);ADAM 17;disintegrin and metalloproteinase domain-containing protein 17;TACE;TNF-alpha convertase;TNF-alpha-converting enzyme.
Konjugat:
Unconjugated
Konzentration:
200 ug/mL (prior to lyoph)
Weitere Details:
Cleaves the membrane-bound precursor of TNF-alpha to its mature soluble form. Responsible for the proteolytical release of soluble JAM3 from endothelial cells surface (By similarity). Responsible for the proteolytic release of several other cell-surface proteins; including p75 TNF-receptor; interleukin 1 receptor type II; p55 TNF-receptor; transforming growth factor-alpha; L-selectin; growth hormone receptor; MUC1 and the amyloid precursor protein. Acts as an activator of Notch pathway by mediating cleavage of Notch; generating the membrane-associated intermediate fragment called Notch extracellular truncation (NEXT). Plays a role in the proteolytic processing of ACE2 (By similarity).
Gendetails:
ADAM metallopeptidase domain 17
Host:
E. coli
Molekulargewicht:
30kDa
Proteindetails:
Disintegrin and metalloproteinase domain-containing protein 17
Reinheit:
>95%
Versandbedingungen:
Blue Ice
Quelle:
E.coli
Lagerbedingungen:
2Â[o]C to 8Â[o]C|-80Â[o]C
Hersteller:
Aviva Systems Biology
Typ:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins