AATF Recombinant Protein
Produktgrößen
10ug
£261,00
OPCD00998-10UG
50ug
£500,00
OPCD00998-50UG
200ug
£901,00
OPCD00998-200UG
Über dieses Produkt
- SKU:
- OPCD00998
- Zusätzliche Namen:
- Apoptosis-antagonizing transcription factor;BFR2;CHE1;CHE-1;DED;protein AATF;rb-binding protein Che-1.
- Konjugat:
- Unconjugated
- Konzentration:
- 200 ug/mL (prior to lyoph)
- Weitere Details:
- May function as a general inhibitor of the histone deacetylase HDAC1. Binding to the pocket region of RB1 may displace HDAC1 from RB1/E2F complexes; leading to activation of E2F target genes and cell cycle progression. Conversely; displacement of HDAC1 from SP1 bound to the CDKN1A promoter leads to increased expression of this CDK inhibitor and blocks cell cycle progression. Also antagonizes PAWR mediated induction of aberrant amyloid peptide production in Alzheimer disease (presenile and senile dementia); although the molecular basis for this phenomenon has not been described to date.
- Gendetails:
- apoptosis antagonizing transcription factor
- Host:
- E. coli
- Molekulargewicht:
- 54kDa
- Proteindetails:
- Protein AATF
- Reinheit:
- > 95%
- Versandbedingungen:
- Blue Ice
- Quelle:
- E.coli
- Lagerbedingungen:
- 2Â[o]C to 8Â[o]C|-80Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Datenblatt des Herstellers:html_datasheet.php