CISH Recombinant Protein
Produktgrößen
10ug
£257,00
OPCD00826-10UG
50ug
£489,00
OPCD00826-50UG
200ug
£879,00
OPCD00826-200UG
Über dieses Produkt
- SKU:
- OPCD00826
- Zusätzliche Namen:
- C;CI;Cis;CIS1;CIS-1;cytokine-inducible SH2 protein;cytokine-inducible SH2-containing protein;F17;F23;SOCS;suppressor of cytokine signaling.
- Konjugat:
- Unconjugated
- Konzentration:
- 200 ug/mL (prior to lyoph)
- Weitere Details:
- SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. CIS is involved in the negative regulation of cytokines that signal through the JAK-STAT5 pathway such as erythropoietin; prolactin and interleukin 3 (IL3) receptor. Inhibits STAT5 trans-activation by suppressing its tyrosine phosphorylation. May be a substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity).
- Gendetails:
- cytokine inducible SH2-containing protein
- Host:
- E. coli
- Molekulargewicht:
- 25kDa
- Proteindetails:
- Cytokine-inducible SH2-containing protein
- Reinheit:
- > 90%
- Versandbedingungen:
- Blue Ice
- Quelle:
- E.coli
- Lagerbedingungen:
- 2Â[o]C to 8Â[o]C|-80Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Datenblatt des Herstellers:html_datasheet.php