CSK Recombinant Protein
Produktgrößen
10ug
£207,00
OPCD00760-10UG
50ug
£366,00
OPCD00760-50UG
200ug
£636,00
OPCD00760-200UG
Über dieses Produkt
- SKU:
- OPCD00760
- Zusätzliche Namen:
- CSK; non-receptor tyrosine kinase;C-Src kinase;c-src tyrosine kinase;protein-tyrosine kinase CYL;tyrosine-protein kinase CSK.
- Konjugat:
- Unconjugated
- Konzentration:
- 200 ug/mL (prior to lyoph)
- Weitere Details:
- Non-receptor tyrosine-protein kinase that plays an important role in the regulation of cell growth; differentiation; migration and immune response. Phosphorylates tyrosine residues located in the C-terminal tails of Src-family kinases (SFKs) including LCK; SRC; HCK; FYN; LYN or YES1. Upon tail phosphorylation; Src-family members engage in intramolecular interactions between the phosphotyrosine tail and the SH2 domain that result in an inactive conformation. To inhibit SFKs; CSK is recruited to the plasma membrane via binding to transmembrane proteins or adapter proteins located near the plasma membrane. Suppresses signaling by various surface receptors; including T-cell receptor (TCR) and B-cell receptor (BCR) by phosphorylating and maintaining inactive several positive effectors such as FYN or LCK.
- Gendetails:
- C-terminal Src kinase
- Host:
- E. coli
- Molekulargewicht:
- 27kDa
- Proteindetails:
- Tyrosine-protein kinase CSK
- Reinheit:
- > 95%
- Versandbedingungen:
- Blue Ice
- Quelle:
- E.coli
- Lagerbedingungen:
- 2Â[o]C to 8Â[o]C|-80Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Datenblatt des Herstellers:html_datasheet.php