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Proteine und Peptide

DMPK Recombinant Protein

Produktgrößen
10ug
£240,00
OPCD00606-10UG
50ug
£452,00
OPCD00606-50UG
200ug
£799,00
OPCD00606-200UG
Über dieses Produkt
SKU:
OPCD00606
Zusätzliche Namen:
DM;DM protein kinase;DM1;DM1 protein kinase;DM1PK;DMK;DM-kinase;DMPK;dystrophia myotonica protein kinase;MDPK;MT-PK;myotonic dystrophy associated protein kinase;Myotonic dystrophy protein kinase;myotonin protein kinase A;myotonin-protein kinase;thymopoietin homolog.
Konjugat:
Unconjugated
Konzentration:
200 ug/mL (prior to lyoph)
Weitere Details:
Non-receptor serine/threonine protein kinase which is necessary for the maintenance of skeletal muscle structure and function. May play a role in myocyte differentiation and survival by regulating the integrity of the nuclear envelope and the expression of muscle-specific genes. May also phosphorylate PPP1R12A and inhibit the myosin phosphatase activity to regulate myosin phosphorylation. Also critical to the modulation of cardiac contractility and to the maintenance of proper cardiac conduction activity probably through the regulation of cellular calcium homeostasis. Phosphorylates PLN; a regulator of calcium pumps and may regulate sarcoplasmic reticulum calcium uptake in myocytes. May also phosphorylate FXYD1/PLM which is able to induce chloride currents. May also play a role in synaptic plasticity.
Gendetails:
DM1 protein kinase
Host:
E. coli
Molekulargewicht:
27kDa
Proteindetails:
Myotonin-protein kinase
Reinheit:
> 95%
Versandbedingungen:
Blue Ice
Quelle:
E.coli
Lagerbedingungen:
2Â[o]C to 8Â[o]C|-80Â[o]C
Hersteller:
Aviva Systems Biology
Typ:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins