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Proteine und Peptide

CISH Recombinant Protein

Produktgrößen
10ug
£192,00
OPCD00569-10UG
50ug
£333,00
OPCD00569-50UG
200ug
£561,00
OPCD00569-200UG
Über dieses Produkt
SKU:
OPCD00569
Zusätzliche Namen:
BACTS2;CIS;CIS-1;cytokine-inducible inhibitor of signaling type 1B;cytokine-inducible SH2-containing protein;G18;Protein G18;SOCS;suppressor of cytokine signaling.
Konjugat:
Unconjugated
Konzentration:
200 ug/mL (prior to lyoph)
Weitere Details:
SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. CIS is involved in the negative regulation of cytokines that signal through the JAK-STAT5 pathway such as erythropoietin; prolactin and interleukin 3 (IL3) receptor. Inhibits STAT5 trans-activation by suppressing its tyrosine phosphorylation. May be a substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity).
Gendetails:
cytokine inducible SH2 containing protein
Host:
E. coli
Molekulargewicht:
39kDa
Proteindetails:
Cytokine-inducible SH2-containing protein
Reinheit:
> 90%
Versandbedingungen:
Blue Ice
Quelle:
E.coli
Lagerbedingungen:
2Â[o]C to 8Â[o]C|-80Â[o]C
Hersteller:
Aviva Systems Biology
Typ:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins