EED Recombinant Protein
Produktgrößen
10ug
£207,00
OPCD00541-10UG
50ug
£366,00
OPCD00541-50UG
200ug
£636,00
OPCD00541-200UG
Über dieses Produkt
- SKU:
- OPCD00541
- Zusätzliche Namen:
- COGIS;embryonic ectoderm development protein;HEED;polycomb protein EED;WAIT1;WD protein associating with integrin cytoplasmic tails 1.
- Konjugat:
- Unconjugated
- Konzentration:
- 200 ug/mL (prior to lyoph)
- Weitere Details:
- Polycomb group (PcG) protein. Component of the PRC2/EED-EZH2 complex; which methylates 'Lys-9' and 'Lys-27' of histone H3; leading to transcriptional repression of the affected target gene. Also recognizes 'Lys-26' trimethylated histone H1 with the effect of inhibiting PRC2 complex methyltransferase activity on nucleosomal histone H3 'Lys-27'; whereas H3 'Lys-27' recognition has the opposite effect; enabling the propagation of this repressive mark. The PRC2/EED-EZH2 complex may also serve as a recruiting platform for DNA methyltransferases; thereby linking two epigenetic repression systems. Genes repressed by the PRC2/EED-EZH2 complex include HOXC8; HOXA9; MYT1 and CDKN2A.
- Gendetails:
- embryonic ectoderm development
- Host:
- E. coli
- Molekulargewicht:
- 38kDa
- Proteindetails:
- Polycomb protein EED
- Reinheit:
- > 90%
- Versandbedingungen:
- Blue Ice
- Quelle:
- E.coli
- Lagerbedingungen:
- 2Â[o]C to 8Â[o]C|-80Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Datenblatt des Herstellers:html_datasheet.php