ALOX12B Recombinant Protein
Produktgrößen
10ug
£240,00
OPCD00141-10UG
50ug
£452,00
OPCD00141-50UG
200ug
£803,00
OPCD00141-200UG
Über dieses Produkt
- SKU:
- OPCD00141
- Zusätzliche Namen:
- 12R-;12R-lipoxygenase;12R-LOX;Alo;Aloxe2;arachidonate 12-lipoxygenase; 12R-type;e-LO;e-LOX2;epidermis-type lipoxygenase 12;epidermis-type lipoxygenase 2.
- Konjugat:
- Unconjugated
- Konzentration:
- 200 ug/mL (prior to lyoph)
- Weitere Details:
- Non-heme iron-containing dioxygenase that catalyzes the stereo-specific peroxidation of free and esterified polyunsaturated fatty acids generating a spectrum of bioactive lipid mediators. Mainly converts arachidonic acid to (12R)-hydroperoxyeicosatetraenoic acid/(12R)-HPETE and minor stereoisomers. In the skin; acts upstream of ALOXE3 on the lineolate moiety of esterified omega-hydroxyacyl-sphingosine (EOS) ceramides to produce an epoxy-ketone derivative; a crucial step in the conjugation of omega-hydroxyceramide to membrane proteins. Therefore plays a crucial role in the synthesis of corneocytes lipid envelope and the establishment of the skin barrier to water loss. May also play a role in the regulation of the expression of airway mucins.
- Gendetails:
- arachidonate 12-lipoxygenase; 12R type
- Host:
- E. coli
- Molekulargewicht:
- 37kDa
- Proteindetails:
- Arachidonate 12-lipoxygenase; 12R-type
- Reinheit:
- > 90%
- Versandbedingungen:
- Blue Ice
- Quelle:
- E.coli
- Lagerbedingungen:
- 2Â[o]C to 8Â[o]C|-80Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Datenblatt des Herstellers:html_datasheet.php