DTNBP1 Recombinant Protein
Produktgrößen
10ug
£225,00
OPCD00123-10UG
50ug
£409,00
OPCD00123-50UG
200ug
£712,00
OPCD00123-200UG
Über dieses Produkt
- SKU:
- OPCD00123
- Zusätzliche Namen:
- 5430437B18Rik;AW048963;biogenesis of lysosome-related organelles complex 1 subunit 8;Bloc;BLOC-1 subunit 8;Bloc1s8;dysb;dysbindin;dysbindin-1;Dystrobrevin-binding protein 1;hermansky-Pudlak syndrome 7 protein homolog;HPS7 protein homolog;sandy;sd;sdy.
- Konjugat:
- Unconjugated
- Konzentration:
- 200 ug/mL (prior to lyoph)
- Weitere Details:
- Component of the BLOC-1 complex; a complex that is required for normal biogenesis of lysosome-related organelles (LRO); such as platelet dense granules and melanosomes. In concert with the AP-3 complex; the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex; in association with SNARE proteins; is also proposed to be involved in neurite extension. Associates with the BLOC-2 complex to facilitate the transport of TYRP1 independent of AP-3 function. Plays a role in synaptic vesicle trafficking and in neurotransmitter release. Plays a role in the regulation of cell surface exposure of DRD2. May play a role in actin cytoskeleton reorganization and neurite outgrowth. May modulate MAPK8 phosphorylation. Appears to promote neuronal transmission and viability through regulating the expression of SNAP25 and SYN1; modulating PI3-kinase-Akt signaling and influencing glutamatergic release. Regulates the expression of SYN1 through binding to its promoter. Modulates prefrontal cortical activity via the dopamine/D2 pathway.
- Gendetails:
- dystrobrevin binding protein 1
- Host:
- E. coli
- Molekulargewicht:
- 25kDa
- Proteindetails:
- Dysbindin
- Reinheit:
- > 95%
- Versandbedingungen:
- Blue Ice
- Quelle:
- E.coli
- Lagerbedingungen:
- 2Â[o]C to 8Â[o]C|-80Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Datenblatt des Herstellers:html_datasheet.php