DPP4 Recombinant Protein
Produktgrößen
20ug
£1085,00
OPCA05344-20UG
100ug
£1384,00
OPCA05344-100UG
Über dieses Produkt
- SKU:
- OPCA05344
- Zusätzliche Namen:
- Cd26;dipeptidyl peptidase 4;dipeptidyl peptidase IV;Dpp;DPP IV;Dpp-4;T-cell activation antigen CD26;THA;THAM;thymocyte-activating molecule.
- Weitere Details:
- Cell surface glycoprotein receptor involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Acts as a positive regulator of T-cell coactivation; by binding at least ADA; CAV1; IGF2R; and PTPRC. Its binding to CAV1 and CARD11 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Its interaction with ADA also regulates lymphocyte-epithelial cell adhesion. In association with FAP is involved in the pericellular proteolysis of the extracellular matrix (ECM); the migration and invasion of endothelial cells into the ECM. May be involved in the promotion of lymphatic endothelial cells adhesion; migration and tube formation. When overexpressed; enhanced cell proliferation; a process inhibited by GPC3. Acts also as a serine exopeptidase with a dipeptidyl peptidase activity that regulates various physiological processes by cleaving peptides in the circulation; including many chemokines; mitogenic growth factors; neuropeptides and peptide hormones. Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline.
- Gendetails:
- dipeptidylpeptidase 4
- Molekulargewicht:
- 100.5 kDa
- Proteindetails:
- Dipeptidyl peptidase 4
- Reinheit:
- Greater than 90% as determined by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Quelle:
- E.coli
- Lagerbedingungen:
- -20Â[o]C or -80Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Datenblatt des Herstellers:html_datasheet.php