CSE1L Recombinant Protein
Produktgrößen
20ug
£1085,00
OPCA05337-20UG
100ug
£1384,00
OPCA05337-100UG
Über dieses Produkt
- SKU:
- OPCA05337
- Zusätzliche Namen:
- CAS;cellular apoptosis susceptibility protein;chromosome segregation 1-like protein;CSE1;CSE1 chromosome segregation 1-like;epididymis secretory sperm binding protein;exp2;exportin-2;importin-alpha re-exporter;XPO2.
- Weitere Details:
- Export receptor for importin-alpha. Mediates importin-alpha re-export from the nucleus to the cytoplasm after import substrates (cargos) have been released into the nucleoplasm. In the nucleus binds cooperatively to importin-alpha and to the GTPase Ran in its active GTP-bound form. Docking of this trimeric complex to the nuclear pore complex (NPC) is mediated through binding to nucleoporins. Upon transit of a nuclear export complex into the cytoplasm; disassembling of the complex and hydrolysis of Ran-GTP to Ran-GDP (induced by RANBP1 and RANGAP1; respectively) cause release of the importin-alpha from the export receptor. CSE1L/XPO2 then return to the nuclear compartment and mediate another round of transport. The directionality of nuclear export is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus.
- Gendetails:
- chromosome segregation 1 like
- Molekulargewicht:
- 39.1 kDa
- Proteindetails:
- Exportin-2
- Reinheit:
- Greater than 90% as determined by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Quelle:
- E.coli
- Lagerbedingungen:
- -20Â[o]C or -80Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Datenblatt des Herstellers:html_datasheet.php