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Proteine und Peptide

GZMA Recombinant Protein

Produktgrößen
20ug
£463,00
OPCA05093-20UG
100ug
£652,00
OPCA05093-100UG
1mg
£2446,00
OPCA05093-1MG
Über dieses Produkt
SKU:
OPCA05093
Zusätzliche Namen:
autocrine thymic lymphoma granzyme-like serine protease;AW494114;BLT esterase;Ctl;Ctla;Ctla3;Ctla-3;fragmentin-1;granzyme A;H factor;Hanukah factor;Hf;Hf1;SE;SE1;serine esterase 1;t cell-specific serine protease 1;TS;TSP;TSP1;TSP-1.
Weitere Details:
Abundant protease in the cytosolic granules of cytotoxic T-cells and NK-cells which activates caspase-independent cell death with morphological features of apoptosis when delivered into the target cell through the immunological synapse. It cleaves after Lys or Arg. Cleaves APEX1 after 'Lys-31' and destroys its oxidative repair activity. Cleaves the nucleosome assembly protein SET after 'Lys-189'; which disrupts its nucleosome assembly activity and allows the SET complex to translocate into the nucleus to nick and degrade the DNA (By similarity).
Gendetails:
granzyme A
Molekulargewicht:
39.6 kDa
Proteindetails:
Granzyme A
Reinheit:
Greater than 90% as determined by SDS-PAGE.
Versandbedingungen:
Blue Ice
Quelle:
E.coli
Lagerbedingungen:
-20Â[o]C or -80Â[o]C
Hersteller:
Aviva Systems Biology
Typ:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins