CREB3L2 Recombinant Protein
Produktgrößen
20ug
£348,00
OPCA04822-20UG
100ug
£500,00
OPCA04822-100UG
1mg
£1822,00
OPCA04822-1MG
Über dieses Produkt
- SKU:
- OPCA04822
- Zusätzliche Namen:
- basic transcription factor 2;BBF2 human homolog on chromosome 7;BBF2H7;B-ZIB transcription factor;cAMP-responsive element-binding protein 3-like protein 2;cyclic AMP-responsive element-binding protein 3-like protein 2;FUS/BBF2H7 protein;TCAG_1951439.
- Weitere Details:
- Transcription factor involved in unfolded protein response (UPR). In the absence of endoplasmic reticulum (ER) stress; inserted into ER membranes; with N-terminal DNA-binding and transcription activation domains oriented toward the cytosolic face of the membrane. In response to ER stress; transported to the Golgi; where it is cleaved in a site-specific manner by resident proteases S1P/MBTPS1 and S2P/MBTPS2. The released N-terminal cytosolic domain is translocated to the nucleus to effect transcription of specific target genes. Plays a critical role in chondrogenesis by activating the transcription of SEC23A; which promotes the transport and secretion of cartilage matrix proteins; and possibly that of ER biogenesis-related genes (By similarity). In a neuroblastoma cell line; protects cells from ER stress-induced death (PubMed:17178827). In vitro activates transcription of target genes via direct binding to the CRE site (PubMed:17178827).
- Gendetails:
- cAMP responsive element binding protein 3 like 2
- Molekulargewicht:
- 54.6 kDa
- Proteindetails:
- Cyclic AMP-responsive element-binding protein 3-like protein 2
- Reinheit:
- Greater than 90% as determined by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Quelle:
- E.coli
- Lagerbedingungen:
- -20Â[o]C or -80Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Datenblatt des Herstellers:html_datasheet.php