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Proteine und Peptide

CRBN Recombinant Protein

Produktgrößen
20ug
£463,00
OPCA04681-20UG
100ug
£647,00
OPCA04681-100UG
Über dieses Produkt
SKU:
OPCA04681
Zusätzliche Namen:
2610203G15Rik;2900045O07Rik;AF229032;AW108261;novel lethal;piL;protein cereblon;protein PiL.
Weitere Details:
Substrate recognition component of a DCX (DDB1-CUL4-X-box) E3 protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins; such as MEIS2. Normal degradation of key regulatory proteins is required for normal limb outgrowth and expression of the fibroblast growth factor FGF8 (By similarity). May play a role in memory and learning by regulating the assembly and neuronal surface expression of large-conductance calcium-activated potassium channels in brain regions involved in memory and learning via its interaction with KCNT1 (By similarity).
Gendetails:
cereblon
Molekulargewicht:
54.9 kDa
Proteindetails:
Protein cereblon
Reinheit:
Greater than 90% as determined by SDS-PAGE.
Versandbedingungen:
Blue Ice
Quelle:
Yeast
Lagerbedingungen:
-20Â[o]C or -80Â[o]C
Hersteller:
Aviva Systems Biology
Typ:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins