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Proteine und Peptide

ERAP1 Recombinant Protein

Produktgrößen
20ug
£463,00
OPCA04658-20UG
100ug
£652,00
OPCA04658-100UG
1mg
£2446,00
OPCA04658-1MG
Über dieses Produkt
SKU:
OPCA04658
Zusätzliche Namen:
adipocyte-derived leucine aminopeptidase;A-LAP;aminopeptidase PILS;Ar;Arts1;ARTS-1;E;endoplasmic reticulum aminopeptidase 1;ERAAP;PILSA;PILSAP;puromycin-insensitive leucyl-specific aminopeptidase;type 1 tumor necrosis factor receptor shedding aminopeptidase regulator;VEGF-induced aminopeptidase.
Weitere Details:
Aminopeptidase that plays a central role in peptide trimming; a step required for the generation of most HLA class I-binding peptides. Peptide trimming is essential to customize longer precursor peptides to fit them to the correct length required for presentation on MHC class I molecules. Strongly prefers substrates 9-16 residues long. Rapidly degrades 13-mer to a 9-mer and then stops. Preferentially hydrolyzes the residue Leu and peptides with a hydrophobic C-terminus; while it has weak activity toward peptides with charged C-terminus. May play a role in the inactivation of peptide hormones. May be involved in the regulation of blood pressure through the inactivation of angiotensin II and/or the generation of bradykinin in the kidney (By similarity).
Gendetails:
endoplasmic reticulum aminopeptidase 1
Molekulargewicht:
28.3 kDa
Proteindetails:
Endoplasmic reticulum aminopeptidase 1
Reinheit:
Greater than 90% as determined by SDS-PAGE.
Versandbedingungen:
Blue Ice
Quelle:
E.coli
Lagerbedingungen:
-20Â[o]C or -80Â[o]C
Hersteller:
Aviva Systems Biology
Typ:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins