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Proteine und Peptide

Delta-actitoxin-Avd1c Recombinant Protein

Produktgrößen
100ug
£886,00
OPCA04633-100UG
1mg
£2912,00
OPCA04633-1MG
Über dieses Produkt
SKU:
OPCA04633
Zusätzliche Namen:
Anemonia sulcata toxin 2;ATX-II;Neurotoxin 2;Toxin II.
Weitere Details:
Binds specifically to voltage-gated sodium channels (Nav) (site 3); thereby delaying their inactivation. Has a strong effect on crustaceans and insects (DmNav1) and a weaker effect on mammals. This toxin is highly potent at mammalian Nav1.1/SCN1A (EC(50)=6.01 nM) and Nav1.2/SCN2A (EC(50)=7.88 nM) (PubMed:15169781). It has also great activity on Nav1.5/SCN5A (EC(50)=49.05 nM); Nav1.4/SCN4A (EC(50)=109.49 nM) and Nav1.6/SCN8A (EC(50)=about 180 nM) and is less potent on Nav1.3/SCN3A (EC(50)=759.22 nM) (when measured as the increase in the slow component) (PubMed:15169781).
Molekulargewicht:
6.9 kDa
Proteindetails:
Delta-actitoxin-Avd1c
Reinheit:
Greater than 90% as determined by SDS-PAGE.
Versandbedingungen:
Blue Ice
Quelle:
Yeast
Lagerbedingungen:
-20Â[o]C or -80Â[o]C
Hersteller:
Aviva Systems Biology
Typ:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins