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Proteine und Peptide

CEACAM6 Recombinant Protein

Produktgrößen
20ug
£348,00
OPCA04475-20UG
100ug
£500,00
OPCA04475-100UG
1mg
£1822,00
OPCA04475-1MG
Über dieses Produkt
SKU:
OPCA04475
Zusätzliche Namen:
carcinoembryonic antigen related cell adhesion molecule 6;carcinoembryonic antigen-related cell adhesion molecule 6;carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen);CD66c;CEAL;Cluster of Differentiation 66c;NCA;Non-specific crossreacting antigen;normal cross-reacting antigen.
Konzentration:
Varies by lot. See vial for exact concentration.
Weitere Details:
Cell surface glycoprotein that plays a role in cell adhesion and tumor progression (PubMed:2803308; PubMed:2022629; PubMed:1378450; PubMed:8776764; PubMed:11590190; PubMed:10910050; PubMed:14724575; PubMed:16204051). Intercellular adhesion occurs in a calcium- and fibronectin-independent manner (PubMed:2022629; PubMed:16204051). Mediates homophilic and heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules; such as CEACAM5 and CEACAM8 (PubMed:2803308; PubMed:2022629; PubMed:8776764; PubMed:11590190; PubMed:16204051). Heterophilic interaction with CEACAM8 occurs in activated neutrophils (PubMed:8776764). Plays a role in neutrophil adhesion to cytokine-activated endothelial cells (PubMed:1378450). Plays a role as an oncogene by promoting tumor progression; positively regulates cell migration; cell adhesion to endothelial cells and cell invasion (PubMed:16204051). Also involved in the metastatic cascade process by inducing gain resistance to anoikis of pancreatic adenocarcinoma and colorectal carcinoma cells (PubMed:10910050; PubMed:14724575).
Gendetails:
CEA cell adhesion molecule 6
Molekulargewicht:
47.2 kDa
Proteindetails:
Carcinoembryonic antigen-related cell adhesion molecule 6
Reinheit:
Greater than 90% as determined by SDS-PAGE.
Aufreinigung:
Affinity purified using IMAC
Versandbedingungen:
Blue Ice
Quelle:
E.coli
Lagerbedingungen:
-20Â[o]C or -80Â[o]C
Hersteller:
Aviva Systems Biology
Typ:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins