CD3G Recombinant Protein
Produktgrößen
20ug
£615,00
OPCA04417-20UG
100ug
£886,00
OPCA04417-100UG
Über dieses Produkt
- SKU:
- OPCA04417
- Zusätzliche Namen:
- CD3 gamma;CD3g molecule; epsilon (CD3-TCR complex);CD3g molecule; gamma (CD3-TCR complex);T-cell receptor T3 gamma chain;T-cell surface glycoprotein CD3 gamma chain.
- Weitere Details:
- Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR); TCR-mediated signals are transmitted across the cell membrane by the CD3 chains CD3D; CD3E; CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement; these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN; resulting in the activation of downstream signaling pathways. In addition to this role of signal transduction in T-cell activation; CD3G plays an essential role in the dynamic regulation of TCR expression at the cell surface. Indeed; constitutive TCR cycling is dependent on the di-leucine-based (diL) receptor-sorting motif present in CD3G.
- Gendetails:
- CD3g molecule
- Molekulargewicht:
- 12.5 kDa
- Proteindetails:
- T-cell surface glycoprotein CD3 gamma chain
- Reinheit:
- Greater than 90% as determined by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Quelle:
- Yeast
- Lagerbedingungen:
- -20Â[o]C or -80Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Datenblatt des Herstellers:html_datasheet.php