FHIT Recombinant Protein
Produktgrößen
20ug
£463,00
OPCA04157-20UG
100ug
£727,00
OPCA04157-100UG
Über dieses Produkt
- SKU:
- OPCA04157
- Zusätzliche Namen:
- AP3A hydrolase;AP3Aase;AW045638;bis(5'-adenosyl)-triphosphatase;diadenosine 5';5'''-P1;P3-triphosphate hydrolase;dinucleosidetriphosphatase;Fra1;Fra14A2;fragile histidine triad protein.
- Weitere Details:
- Cleaves P(1)-P(3)-bis(5'-adenosyl) triphosphate (Ap3A) to yield AMP and ADP. Can also hydrolyze P(1)-P(4)-bis(5'-adenosyl) tetraphosphate (Ap4A); but has extremely low activity with ATP. Modulates transcriptional activation by CTNNB1 and thereby contributes to regulate the expression of genes essential for cell proliferation and survival; such as CCND1 and BIRC5. Plays a role in the induction of apoptosis via SRC and AKT1 signaling pathways. Inhibits MDM2-mediated proteasomal degradation of p53/TP53 and thereby plays a role in p53/TP53-mediated apoptosis. Induction of apoptosis depends on the ability of FHIT to bind P(1)-P(3)-bis(5'-adenosyl) triphosphate or related compounds; but does not require its catalytic activity (By similarity). Functions as tumor suppressor.
- Gendetails:
- fragile histidine triad gene
- Molekulargewicht:
- 19.1 kDa
- Proteindetails:
- Bis(5'-adenosyl)-triphosphatase
- Reinheit:
- Greater than 90% as determined by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Quelle:
- Yeast
- Lagerbedingungen:
- -20Â[o]C or -80Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Datenblatt des Herstellers:html_datasheet.php