EIF3G Recombinant Protein
Produktgrößen
20ug
£348,00
OPCA03847-20UG
100ug
£500,00
OPCA03847-100UG
1mg
£1822,00
OPCA03847-1MG
Über dieses Produkt
- SKU:
- OPCA03847
- Zusätzliche Namen:
- eIF3 p42;eIF3 p44;eIF3-delta;eIF-3-delta;EIF3-P42;eIF3-p44;EIF3S4;eukaryotic translation initiation factor 3 RNA-binding subunit;Eukaryotic translation initiation factor 3 subunit 4;eukaryotic translation initiation factor 3 subunit G;eukaryotic translation initiation factor 3 subunit p42;eukaryotic translation initiation factor 3; subunit 4 delta; 44kDa.
- Weitere Details:
- RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex; which is required for several steps in the initiation of protein synthesis (PubMed:17581632; PubMed:25849773; PubMed:27462815). The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1; eIF-1A; eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation (PubMed:17581632). The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation; including cell cycling; differentiation and apoptosis; and uses different modes of RNA stem-loop binding to exert either translational activation or repression (PubMed:25849773). This subunit can bind 18S rRNA.
- Gendetails:
- eukaryotic translation initiation factor 3 subunit G
- Molekulargewicht:
- 51.5 kDa
- Proteindetails:
- Eukaryotic translation initiation factor 3 subunit G
- Reinheit:
- Greater than 90% as determined by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Quelle:
- E.coli
- Lagerbedingungen:
- -20Â[o]C or -80Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Datenblatt des Herstellers:html_datasheet.php