AaH2 Recombinant Protein
Produktgrößen
20ug
£561,00
OPCA03379-20UG
100ug
£793,00
OPCA03379-100UG
1mg
£2446,00
OPCA03379-1MG
Über dieses Produkt
- SKU:
- OPCA03379
- Zusätzliche Namen:
- AaH II;Neurotoxin 2.
- Weitere Details:
- Alpha toxins bind voltage-independently at site-3 of sodium channels (Nav) and inhibit the inactivation of the activated channels; thereby blocking neuronal transmission. The toxin principally slows the inactivation process of TTX-sensitive sodium channels (PubMed:23685008). It is active on rat brain Nav1.2/SCN2A sodium channel (EC(50)=2.6 nM) and on rat skeletal muscle Nav1.4/SCN4A sodium channel (EC(50)=2.2 nM) (PubMed:12911331); as well as on human neuronal Nav1.7/SCN9A (EC(50)=6.8 nM) (PubMed:23685008). This toxin is active against mammals. In vivo; intraplantar injection into mice induces spontaneous pain responses (PubMed:23685008).
- Molekulargewicht:
- 23.3 kDa
- Proteindetails:
- Alpha-mammal toxin AaH2
- Reinheit:
- Greater than 90% as determined by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Quelle:
- E.coli
- Lagerbedingungen:
- -20Â[o]C or -80Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Datenblatt des Herstellers:html_datasheet.php