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Proteine und Peptide

ARNT Recombinant Protein

Produktgrößen
20ug
£398,00
OPCA02596-20UG
100ug
£550,00
OPCA02596-100UG
Über dieses Produkt
SKU:
OPCA02596
Zusätzliche Namen:
aryl hydrocarbon receptor nuclear translocator;bHLHe2;class E basic helix-loop-helix protein 2;dioxin receptor; nuclear translocator;HIF1B;HIF1-beta;HIF-1beta;HIF-1-beta;HIF1BETA;hypoxia-inducible factor 1; beta subunit;Hypoxia-inducible factor 1-beta;TANGO.
Weitere Details:
Required for activity of the Ah (dioxin) receptor. This protein is required for the ligand-binding subunit to translocate from the cytosol to the nucleus after ligand binding. The complex then initiates transcription of genes involved in the activation of PAH procarcinogens. The heterodimer binds to core DNA sequence 5'-TACGTG-3' within the hypoxia response element (HRE) of target gene promoters and functions as a transcriptional regulator of the adaptive response to hypoxia (By similarity). The heterodimer ARNT:AHR binds to core DNA sequence 5'-TGCGTG-3' within the dioxin response element (DRE) of target gene promoters and activates their transcription (PubMed:28396409).
Gendetails:
aryl hydrocarbon receptor nuclear translocator
Host:
Human
Molekulargewicht:
54.8 kDa
Proteindetails:
Aryl hydrocarbon receptor nuclear translocator
Reinheit:
Greater than 90% as determined by SDS-PAGE.
Versandbedingungen:
Blue Ice
Quelle:
Yeast
Lagerbedingungen:
-20Â[o]C or -80Â[o]C
Hersteller:
Aviva Systems Biology
Typ:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins