DTD2 Recombinant Protein
Produktgrößen
20ug
£348,00
OPCA02412-20UG
100ug
£500,00
OPCA02412-100UG
1mg
£1822,00
OPCA02412-1MG
Über dieses Produkt
- SKU:
- OPCA02412
- Zusätzliche Namen:
- animalia-specifc tRNA deacylase;animalia-specific tRNA deacylase;ATD;C14orf126;D-aminoacyl-tRNA deacylase 2;D-tyrosyl-tRNA deacylase 2 (putative);D-tyrosyl-tRNA(Tyr) deacylase 2;L-alanyl-tRNA deacylase;probable D-tyrosyl-tRNA(Tyr) deacylase 2;putative D-tyrosyl-tRNA deacylase 2;putative D-tyrosyl-tRNA(Tyr) deacylase 2.
- Weitere Details:
- Deacylates mischarged D-aminoacyl-tRNAs (By similarity). Probably acts by rejecting L-amino acids from its binding site rather than specific recognition of D-amino acids (By similarity). Catalyzes the hydrolysis of D-tyrosyl-tRNA(Tyr); has no activity on correctly charged L-tyrosyl-tRNA(Tyr) (By similarity). By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules; this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality. In contrast to DTD1; deacylates L-Ala mischarged on tRNA(Thr)(G4.U69) by alanine-tRNA ligase AARS (PubMed:29410408). Can deacylate L-Ala due to a relaxed specificity for substrate chirality caused by the trans conformation of the Gly-Pro motif in the active site (PubMed:29410408). Also hydrolyzes correctly charged; achiral; glycyl-tRNA(Gly) in vitro; although in vivo EEF1A1/EF-Tu may protect cognate achiral glycyl-tRNA(Gly) from DTD2-mediated deacetylation (By similarity).
- Gendetails:
- D-aminoacyl-tRNA deacylase 2
- Host:
- Human
- Molekulargewicht:
- 34.7 kDa
- Proteindetails:
- D-aminoacyl-tRNA deacylase 2
- Reinheit:
- Greater than 90% as determined by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Quelle:
- E.coli
- Lagerbedingungen:
- -20Â[o]C or -80Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Datenblatt des Herstellers:html_datasheet.php