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Proteine und Peptide

AC1 Recombinant Protein

Produktgrößen
20ug
£561,00
OPCA02023-20UG
100ug
£793,00
OPCA02023-100UG
1mg
£2446,00
OPCA02023-1MG
Über dieses Produkt
SKU:
OPCA02023
Zusätzliche Namen:
40.4 kDa protein;Protein AC1;Protein AL1.
Weitere Details:
Essential for the replication of viral ssDNA. The closed circular ssDNA genome is first converted to a superhelical dsDNA. Rep binds a specific region at the genome origin of replication. It introduces an endonucleolytic nick within the conserved sequence 5'-TAATATTAC-3' in the intergenic region of the genome present in all geminiviruses; thereby initiating the rolling circle replication (RCR). Following cleavage; binds covalently to the 5'-phosphate of DNA as a tyrosyl ester. The cleavage gives rise to a free 3'-OH that serves as a primer for the cellular DNA polymerase. The polymerase synthesizes the (+) strand DNA by rolling circle mechanism. After one round of replication; a Rep-catalyzed nucleotidyl transfer reaction releases a circular single-stranded virus genome; thereby terminating the replication. Displays origin-specific DNA cleavage; nucleotidyl transferase; ATPase and helicase activities (By similarity).
Molekulargewicht:
56.3 kDa
Proteindetails:
Replication-associated protein
Reinheit:
Greater than 90% as determined by SDS-PAGE.
Versandbedingungen:
Blue Ice
Quelle:
E.coli
Lagerbedingungen:
-20Â[o]C or -80Â[o]C
Hersteller:
Aviva Systems Biology
Typ:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins