EYA2 Recombinant Protein
Produktgrößen
20ug
£348,00
OPCA01591-20UG
100ug
£500,00
OPCA01591-100UG
1mg
£1822,00
OPCA01591-1MG
Über dieses Produkt
- SKU:
- OPCA01591
- Zusätzliche Namen:
- EAB1;eyes absent homolog 2.
- Weitere Details:
- Functions both as protein phosphatase and as transcriptional coactivator for SIX1; and probably also for SIX2; SIX4 and SIX5 (PubMed:12500905; PubMed:23435380). Tyrosine phosphatase that dephosphorylates 'Tyr-142' of histone H2AX (H2AXY142ph) and promotes efficient DNA repair via the recruitment of DNA repair complexes containing MDC1. 'Tyr-142' phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress (PubMed:19351884). Its function as histone phosphatase may contribute to its function in transcription regulation during organogenesis. Plays an important role in hypaxial muscle development together with SIX1 and DACH2; in this it is functionally redundant with EYA1 (PubMed:12500905).
- Gendetails:
- EYA transcriptional coactivator and phosphatase 2
- Host:
- Human
- Molekulargewicht:
- 72.7 kDa
- Proteindetails:
- Eyes absent homolog 2
- Reinheit:
- Greater than 90% as determined by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Quelle:
- E.coli
- Lagerbedingungen:
- -20Â[o]C or -80Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Datenblatt des Herstellers:html_datasheet.php