ETHE1 Recombinant Protein
Produktgrößen
20ug
£348,00
OPCA01590-20UG
100ug
£500,00
OPCA01590-100UG
1mg
£1822,00
OPCA01590-1MG
Über dieses Produkt
- SKU:
- OPCA01590
- Zusätzliche Namen:
- ethylmalonic encephalopathy 1;Ethylmalonic encephalopathy protein 1;hepatoma subtracted clone one protein;HSCO;persulfide dioxygenase ETHE1; mitochondrial;protein ETHE1; mitochondrial;sulfur dioxygenase ETHE1;YF13H12.
- Weitere Details:
- Sulfur dioxygenase that plays an essential role in hydrogen sulfide catabolism in the mitochondrial matrix. Hydrogen sulfide (H(2)S) is first oxidized by SQRDL; giving rise to cysteine persulfide residues. ETHE1 consumes molecular oxygen to catalyze the oxidation of the persulfide; once it has been transferred to a thiophilic acceptor; such as glutathione (R-SSH). Plays an important role in metabolic homeostasis in mitochondria by metabolizing hydrogen sulfide and preventing the accumulation of supraphysiological H(2)S levels that have toxic effects; due to the inhibition of cytochrome c oxidase. First described as a protein that can shuttle between the nucleus and the cytoplasm and suppress p53-induced apoptosis by sequestering the transcription factor RELA/NFKB3 in the cytoplasm and preventing its accumulation in the nucleus (PubMed:12398897).
- Gendetails:
- ETHE1 persulfide dioxygenase
- Host:
- Human
- Molekulargewicht:
- 43.1 kDa
- Proteindetails:
- Persulfide dioxygenase ETHE1; mitochondrial
- Reinheit:
- Greater than 90% as determined by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Quelle:
- E.coli
- Lagerbedingungen:
- -20Â[o]C or -80Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Datenblatt des Herstellers:html_datasheet.php