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Proteine und Peptide

EPPK1 Recombinant Protein

Produktgrößen
20ug
£348,00
OPCA01587-20UG
100ug
£500,00
OPCA01587-100UG
1mg
£1822,00
OPCA01587-1MG
Über dieses Produkt
SKU:
OPCA01587
Zusätzliche Namen:
450 kDa epidermal antigen;epidermal autoantigen 450K;EPIPL;EPIPL1;epiplakin.
Weitere Details:
Cytoskeletal linker protein that connects to intermediate filaments and controls their reorganization in response to stress (PubMed:15671067; PubMed:27206504; PubMed:23398049). In response to mechanical stress like wound healing; is associated with the machinery for cellular motility by slowing down keratinocyte migration and proliferation and accelerating keratin bundling in proliferating keratinocytes thus contributing to tissue architecture (PubMed:27206504; PubMed:23398049). However in wound healing in corneal epithelium also positively regulates cell differentiation and proliferation and negatively regulates migration thereby controlling corneal epithelium morphogenesis and integrity. In response to cellular stress; plays a role in keratin filament reorganization; probably by protecting keratin filaments against disruption. During liver and pancreas injuries; plays a protective role by chaperoning disease-induced intermediate filament reorganization (By similarity).
Gendetails:
epiplakin 1
Host:
Human
Molekulargewicht:
27.5 kDa
Proteindetails:
Epiplakin
Reinheit:
Greater than 90% as determined by SDS-PAGE.
Versandbedingungen:
Blue Ice
Quelle:
E.coli
Lagerbedingungen:
-20Â[o]C or -80Â[o]C
Hersteller:
Aviva Systems Biology
Typ:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins