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Proteine und Peptide

ASNA1 Recombinant Protein

Produktgrößen
20ug
£348,00
OPCA01472-20UG
100ug
£500,00
OPCA01472-100UG
1mg
£1822,00
OPCA01472-1MG
Über dieses Produkt
SKU:
OPCA01472
Zusätzliche Namen:
arsA arsenite transporter; ATP-binding; homolog 1;ARSA1;ARSA-I;Arsenical pump-driving ATPase;Arsenite-stimulated ATPase;ASNA1;ASNA-I;ATPase GET3;golgi to ER traffic 3 homolog;hARSA-I;hASNA-I;transmembrane domain recognition complex 40 kDa ATPase subunit;TRC40.
Weitere Details:
ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors; where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state; facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. Subsequently; the homodimer reverts towards the open dimer state; lowering its affinity for the membrane-bound receptor; and returning it to the cytosol to initiate a new round of targeting (By similarity). May be involved in insulin signaling.
Gendetails:
guided entry of tail-anchored proteins factor 3; ATPase
Host:
Human
Molekulargewicht:
54.7 kDa
Proteindetails:
ATPase ASNA1
Reinheit:
Greater than 90% as determined by SDS-PAGE.
Versandbedingungen:
Blue Ice
Quelle:
E.coli
Lagerbedingungen:
-20Â[o]C or -80Â[o]C
Hersteller:
Aviva Systems Biology
Typ:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins