GPI Protein
Produktgrößen
5µg
£186,00
OOPA00164-5UG
Über dieses Produkt
- SKU:
- OOPA00164
- Zusätzliche Namen:
- Glucose-6-phosphate isomerase; Phosphoglucose isomerase; Phosphohexose isomerase; Autocrine motility factor; Neuroleukin; Sperm antigen 36; GPI; PGI; PHI; AMF; NLK; SA-36; GNPI
- Konzentration:
- 1 mg/ml
- Weitere Details:
- GPI Human Recombinant fused with a 20 amino acid His tag at N-terminus produced in E.Coli is a single; non-glycosylated; polypeptide chain containing 578 amino acids (1-558 a.a.). Glucose-6-phosphate isomerase (GPI) is a part of the GPI family whose members encode multifunctional phosphoglucose isomerase proteins involved in energy pathways. GPI is a dimeric enzyme which catalyzes the reversible isomerization of glucose-6-phosphate and fructose-6-phosphate. Mammalian GPI also functions as a tumor-secreted cytokine and an angiogenic factor (AMF) which stimulates endothelial cell motility. In addition; GPI is a neurotrophic factor (Neuroleukin) for spinal and sensory neurons. GPI performs in different capacities inside and outside the cell. In the cytoplasm; GPI is involved in glycolysis and gluconeogenesis; while outside the cell it acts as a neurotrophic factor for spinal and sensory neurons. Defects in the GPI gene cause the nonspherocytic hemolytic anemia and a severe enzyme deficiency can be linked to hydrops fetalis; immediate neonatal death and neurological impairment.
- Molekulargewicht:
- 65.3 kDa
- Reinheit:
- ≥ 95.0% as determined by SDS-PAGE.
- Aufreinigung:
- Purified by proprietary chromatographic techniques
- Versandbedingungen:
- Blue Ice
- Quelle:
- E.coli
- Lagerbedingungen:
- Store at 4C if entire vial will be used within 2-4 weeks. Store; frozen at -20C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Datenblatt des Herstellers:html_datasheet.php