CLSTN1 ELISA Kit
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96 Wells
£814,00
OKEI00311-96WELLS
Über dieses Produkt
- SKU:
- OKEI00311
- Zusätzliche Namen:
- CST-1; CSTN1; CDHR12; PIK3CD; ALC-ALPHA; XB31alpha; alcalpha1; alcalpha2
- Weitere Details:
- Induces KLC1 association with vesicles and functions as a cargo in axonal anterograde transport. Complex formation with APBA2 and APP; stabilizes APP metabolism and enhances APBA2-mediated suppression of beta-APP40 secretion; due to the retardation of intracellular APP maturation. In complex with APBA2 and C99; a C-terminal APP fragment; abolishes C99 interaction with PSEN1 and thus APP C99 cleavage by gamma-secretase; most probably through stabilization of the direct interaction between APBA2 and APP. The intracellular fragment AlcICD suppresses APBB1-dependent transactivation stimulated by APP C-terminal intracellular fragment (AICD); most probably by competing with AICD for APBB1-binding. May modulate calcium-mediated postsynaptic signals.
- Proteindetails:
- Calsyntenin-1
- Empfindlichkeit:
- 0.094 ng/mL
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store as indicated in product manual.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Assay Kits: ELISAs