CHD5 ELISA Kit
Produktgrößen
96 Wells
£814,00
OKEI00162-96WELLS
Über dieses Produkt
- SKU:
- OKEI00162
- Zusätzliche Namen:
- CHD-5
- Weitere Details:
- Chromatin-remodeling protein that binds DNA through histones and regulates gene transcription. May specifically recognize and bind trimethylated 'Lys-27' (H3K27me3) and non-methylated 'Lys-4' of histone H3. Plays a role in the development of the nervous system by activating the expression of genes promoting neuron terminal differentiation. In parallel; it may also positively regulate the trimethylation of histone H3 at 'Lys-27' thereby specifically repressing genes that promote the differentiation into non-neuronal cell lineages. Tumor suppressor; it regulates the expression of genes involved in cell proliferation and differentiation. Downstream activated genes may include CDKN2A that positively regulates the p53/TP53 pathway; which in turn; prevents cell proliferation. In spermatogenesis; it probably regulates histone hyperacetylation and the replacement of histones by transition proteins in chromatin; a crucial step in the condensation of spermatid chromatin and the production of functional spermatozoa.
- Proteindetails:
- Chromodomain-helicase-DNA-binding protein 5
- Empfindlichkeit:
- 11.25 pg/mL
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store as indicated in product manual.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Assay Kits: ELISAs