ATF7 ELISA Kit
Produktgrößen
96 Wells
£814,00
OKEI00140-96WELLS
Über dieses Produkt
- SKU:
- OKEI00140
- Zusätzliche Namen:
- ATFA
- Weitere Details:
- Plays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AG][AG]-3'); a sequence present in many viral and cellular promoters. Activator of the NF-ELAM1/delta-A site of the E-selectin promoter. Has no intrinsic transcriptional activity; but activates transcription on formation of JUN or FOS heterodimers. Also can bind TRE promoter sequences when heterodimerized with members of the JUN family. Isoform 4 acts as a dominant repressor of the E-selectin/NF-ELAM1/delta-A promoter. Isoform 5 acts as a negative regulator; inhibiting both ATF2 and ATF7 transcriptional activities. It may exert these effects by sequestrating in the cytoplasm the Thr-53 phosphorylating kinase; preventing activation.
- Proteindetails:
- Cyclic AMP-dependent transcription factor ATF-7
- Empfindlichkeit:
- 0.094 ng/mL
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store as indicated in product manual.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Assay Kits: ELISAs