Cholylglycine ELISA Kit
Produktgrößen
96 Wells
£788,00
OKEH02529-96WELLS
Über dieses Produkt
- SKU:
- OKEH02529
- Zusätzliche Namen:
- Glycocoholic acid
- Weitere Details:
- erum Cholygllycine (Cholygllycine; CG) is a combination of secondary bile acids with glycine conjugated bile acids; in liver cells; cholesterol; after its complex enzymatic reaction; turn into the primary bile acid. Cholic acid (CA) and chenodeoxycholic acid (the CD-CA). Bile acid steroid nucleus three hydroxyl groups (C3; C7; C12); the side chain hydroxyl at the end of the peptide bond and glycine combined with a molecular weight of 462u. CG normal metabolic pathways of the intestine - liver circulation; CG synthesized by hepatocytes; bile canaliculi; bile duct discharged into the gall bladder; along with the bile into the duodenum to help digestion of food. 95% of bile acid reabsorption in the distal ileum; come back to the liver via the portal vein; and uptake by the liver cells to re-use. Exist in the form of protein binding in serum; the total amount of overflow into the systemic circulation is less than 1%. Under normal circumstances; bile acid content in the peripheral blood; leaving little room for normal adults; whether fasting or postprandial serum CG concentration stabilized at a low level. When liver cells are damaged; the liver cell uptake CG capacity decreased; resulting in increased CG content in the blood; cholestasis; liver excretion of bile acids that barriers to reflux of blood circulation increased CG content; but also to the blood CG levels increased. Therefore; the determination of serum glycocholic acid (SCG) by ELISA method is a sensitive indicator to evaluate the function of liver cells and their hepatobiliary material circulation. Normal serum Cholygllycine: 1.3 ± 0.8mg / L; range 0.4 to 2.98mg / L; and the low limit of the hepatitis diagnosis <3.18mg / L
- Proteindetails:
- Cholylglycine
- Empfindlichkeit:
- 0.5 ng/mL
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store as indicated in product manual.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Assay Kits: ELISAs