ELAVL1 ELISA Kit
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96 Wells
£1070,00
OKCD09220-96WELLS
Über dieses Produkt
- SKU:
- OKCD09220
- Zusätzliche Namen:
- ELAV (embryonic lethal; abnormal vision; Drosophila)-like 1 (Hu antigen R);ELAV like 1;ELAV-like protein 1;Hua;hu-antigen R;HuR;mRNA-stabilizing factor HuR.
- Weitere Details:
- RNA-binding protein that binds to the 3'-UTR region of mRNAs and increases their stability (By similarity). Involved in embryonic stem cells (ESCs) differentiation: preferentially binds mRNAs that are not methylated by N6-methyladenosine (m6A); stabilizing them; promoting ESCs differentiation (By similarity). Binds to poly-U elements and AU-rich elements (AREs) in the 3'-UTR of target mRNAs. Binds avidly to the AU-rich element in FOS and IL3/interleukin-3 mRNAs. In the case of the FOS AU-rich element; binds to a core element of 27 nucleotides that contain AUUUA; AUUUUA; and AUUUUUA motifs. Binds preferentially to the 5'-UUUU[AG]UUU-3' motif in vitro (By similarity). With ZNF385A; binds the 3'-UTR of p53/TP53 mRNA to control their nuclear export induced by CDKN2A. Hence; may regulate p53/TP53 expression and mediate in part the CDKN2A anti-proliferative activity. May also bind with ZNF385A the CCNB1 mRNA (By similarity).
- Gendetails:
- ELAV like RNA binding protein 1
- Proteindetails:
- ELAV-like protein 1
- Empfindlichkeit:
- < 0.066ng/mL
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- 2Â[o]C to 8Â[o]C|-20Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Assay Kits: ELISAs
- Datenblatt des Herstellers:html_datasheet.php