DNMT3B ELISA Kit
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96 Wells
£1016,00
OKCD09165-96WELLS
Über dieses Produkt
- SKU:
- OKCD09165
- Zusätzliche Namen:
- DNA (cytosine-5-)-methyltransferase 3 beta;DNA (cytosine-5)-methyltransferase 3B;DNA cytosine-5--methyltransferase 3 beta;DNA methyltransferase HsaIIIB;DNA MTase HsaIIIB;FSHD4;ICF;ICF1;M.HsaIIIB.
- Weitere Details:
- Required for genome-wide de novo methylation and is essential for the establishment of DNA methylation patterns during development. DNA methylation is coordinated with methylation of histones. May preferentially methylates nucleosomal DNA within the nucleosome core region. May function as transcriptional co-repressor by associating with CBX4 and independently of DNA methylation. Seems to be involved in gene silencing (By similarity). In association with DNMT1 and via the recruitment of CTCFL/BORIS; involved in activation of BAG1 gene expression by modulating dimethylation of promoter histone H3 at H3K4 and H3K9. Isoforms 4 and 5 are probably not functional due to the deletion of two conserved methyltransferase motifs. Function as transcriptional corepressor by associating with ZHX1. Required for DUX4 silencing in somatic cells (PubMed:27153398).
- Gendetails:
- DNA methyltransferase 3 beta
- Proteindetails:
- DNA (cytosine-5)-methyltransferase 3B
- Empfindlichkeit:
- < 0.112ng/mL
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- 2Â[o]C to 8Â[o]C|-20Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Assay Kits: ELISAs
- Datenblatt des Herstellers:html_datasheet.php