E2F1 ELISA Kit
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96 Wells
£1016,00
OKCD09155-96WELLS
Über dieses Produkt
- SKU:
- OKCD09155
- Zusätzliche Namen:
- E2F-1;PBR3;PRB-binding protein E2F-1;RBAP1;RBAP-1;RBBP3;RBBP-3;RBP3;retinoblastoma-associated protein 1;retinoblastoma-binding protein 3;transcription factor E2F1.
- Weitere Details:
- Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site; 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F1 binds preferentially RB1 in a cell-cycle dependent manner. It can mediate both cell proliferation and TP53/p53-dependent apoptosis. Blocks adipocyte differentiation by binding to specific promoters repressing CEBPA binding to its target gene promoters (PubMed:20176812). Positively regulates transcription of RRP1B (PubMed:20040599).
- Gendetails:
- E2F transcription factor 1
- Proteindetails:
- Transcription factor E2F1
- Empfindlichkeit:
- < 0.054g/mL
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- 2Â[o]C to 8Â[o]C|-20Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Assay Kits: ELISAs
- Datenblatt des Herstellers:html_datasheet.php