AIM2 ELISA Kit
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96 Wells
£1016,00
OKCD08905-96WELLS
Über dieses Produkt
- SKU:
- OKCD08905
- Zusätzliche Namen:
- Absent in melanoma 2;interferon-inducible protein AIM2;PYHIN4.
- Weitere Details:
- Involved in innate immune response by recognizing cytosolic double-stranded DNA and inducing caspase-1-activating inflammasome formation in macrophages. Upon binding to DNA is thought to undergo oligomerization and to associate with PYCARD initiating the recruitment of caspase-1 precusrsor and processing of interleukin-1 beta and interleukin-18. Detects cytosolic dsDNA of viral and bacterial origin in a non-sequence-specific manner. Can also trigger PYCARD-dependent; caspase-1-independent cell death that involves caspase-8 (By similarity). Tumor suppressor which may act by repressing NF-kappa-B transcriptional activity.
- Gendetails:
- absent in melanoma 2
- Proteindetails:
- Interferon-inducible protein AIM2
- Empfindlichkeit:
- < 0.063ng/mL
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- 2Â[o]C to 8Â[o]C|-20Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Assay Kits: ELISAs
- Datenblatt des Herstellers:html_datasheet.php