FZD1 ELISA Kit
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96 Wells
£1016,00
OKCD08669-96WELLS
Über dieses Produkt
- SKU:
- OKCD08669
- Zusätzliche Namen:
- frizzled 1; seven transmembrane spanning receptor;frizzled family receptor 1;frizzled homolog 1;frizzled; Drosophila; homolog of; 1;frizzled-1;fz-1;fzE1;hFz1;Wnt receptor.
- Weitere Details:
- Receptor for Wnt proteins (PubMed:10557084). Activated by WNT3A; WNT3; WNT1 and to a lesser extent WNT2; but apparently not by WNT4; WNT5A; WNT5B; WNT6; WNT7A or WNT7B (PubMed:10557084). Contradictory results showing activation by WNT7B have been described for mouse (By similarity). Functions in the canonical Wnt/beta-catenin signaling pathway (PubMed:10557084). The canonical Wnt/beta-catenin signaling pathway leads to the activation of disheveled proteins; inhibition of GSK-3 kinase; nuclear accumulation of beta-catenin and activation of Wnt target genes (PubMed:10557084). A second signaling pathway involving PKC and calcium fluxes has been seen for some family members; but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway; as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues (Probable).
- Gendetails:
- frizzled class receptor 1
- Proteindetails:
- Frizzled-1
- Empfindlichkeit:
- < 0.053ng/mL
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- 2Â[o]C to 8Â[o]C|-20Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Assay Kits: ELISAs
- Datenblatt des Herstellers:html_datasheet.php