CUBN ELISA Kit
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96 Wells
£1070,00
OKCD08116-96WELLS
Über dieses Produkt
- SKU:
- OKCD08116
- Zusätzliche Namen:
- 460 kDa receptor;cubilin;glycoprotein 280;GP280;IFCR;intrinsic factor-cobalamin receptor;intrinsic factor-vitamin B12 receptor;MGA1.
- Weitere Details:
- Cotransporter which plays a role in lipoprotein; vitamin and iron metabolism; by facilitating their uptake. Binds to ALB; MB; Kappa and lambda-light chains; TF; hemoglobin; GC; SCGB1A1; APOA1; high density lipoprotein; and the GIF-cobalamin complex. The binding of all ligands requires calcium. Serves as important transporter in several absorptive epithelia; including intestine; renal proximal tubules and embryonic yolk sac. Interaction with LRP2 mediates its trafficking throughout vesicles and facilitates the uptake of specific ligands like GC; hemoglobin; ALB; TF and SCGB1A1. Interaction with AMN controls its trafficking to the plasma membrane and facilitates endocytosis of ligands. May play an important role in the development of the peri-implantation embryo through internalization of APOA1 and cholesterol. Binds to LGALS3 at the maternal-fetal interface.
- Gendetails:
- cubilin
- Proteindetails:
- Cubilin
- Empfindlichkeit:
- < 0.114ng/mL
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- 2Â[o]C to 8Â[o]C|-20Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Assay Kits: ELISAs
- Datenblatt des Herstellers:html_datasheet.php