FLT4 ELISA Kit
Produktgrößen
96 Wells
£1042,00
OKCD07774-96WELLS
Über dieses Produkt
- SKU:
- OKCD07774
- Zusätzliche Namen:
- FLT-4;FMS-like tyrosine kinase 4;fms-related tyrosine kinase 4;tyrosine-protein kinase receptor FLT4;vascular endothelial growth factor receptor 3;Vegfr3;VEGFR-3.
- Weitere Details:
- Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFC and VEGFD; and plays an essential role in adult lymphangiogenesis and in the development of the vascular network and the cardiovascular system during embryonic development. Promotes proliferation; survival and migration of endothelial cells; and regulates angiogenic sprouting. Signaling by activated FLT4 leads to enhanced production of VEGFC; and to a lesser degree VEGFA; thereby creating a positive feedback loop that enhances FLT4 signaling. Modulates KDR signaling by forming heterodimers. Mediates activation of the MAPK1/ERK2; MAPK3/ERK1 signaling pathway; of MAPK8 and the JUN signaling pathway; and of the AKT1 signaling pathway. Phosphorylates SHC1. Mediates phosphorylation of PIK3R1; the regulatory subunit of phosphatidylinositol 3-kinase. Promotes phosphorylation of MAPK8 at 'Thr-183' and 'Tyr-185'; and of AKT1 at 'Ser-473' (By similarity).
- Gendetails:
- Fms related receptor tyrosine kinase 4
- Proteindetails:
- Vascular endothelial growth factor receptor 3
- Empfindlichkeit:
- < 0.064ng/mL
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- 2Â[o]C to 8Â[o]C|-20Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Assay Kits: ELISAs
- Datenblatt des Herstellers:html_datasheet.php