ERBB2 ELISA Kit
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96 Wells
£842,00
OKCD07746-96WELLS
Über dieses Produkt
- SKU:
- OKCD07746
- Zusätzliche Namen:
- avian erythroblastosis oncogene B 2;c-erbB;c-erbB2;c-erbB-2;c-ne;c-neu;ErbB-;Erbb-2;HER;HER-;HER2;HER-2;l11Ju;l11Jus8;mKIAA3023;Ne;Neu;Neu oncogene;p185erbB2;proto-oncogene c-ErbB-2;proto-oncogene NEU;receptor tyrosine-protein kinase erbB-2;v-erb-b2 erythroblastic leukemia viral oncogene homolog 2; neuro/glioblastoma derived oncogene homolog.
- Weitere Details:
- Protein tyrosine kinase that is part of several cell surface receptor complexes; but that apparently needs a coreceptor for ligand binding. Essential component of a neuregulin-receptor complex; although neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. Regulates outgrowth and stabilization of peripheral microtubules (MTs). Upon ERBB2 activation; the MEMO1-RHOA-DIAPH1 signaling pathway elicits the phosphorylation and thus the inhibition of GSK3B at cell membrane. This prevents the phosphorylation of APC and CLASP2; allowing its association with the cell membrane. In turn; membrane-bound APC allows the localization of MACF1 to the cell membrane; which is required for microtubule capture and stabilization (By similarity).
- Gendetails:
- erb-b2 receptor tyrosine kinase 2
- Proteindetails:
- Receptor tyrosine-protein kinase erbB-2
- Empfindlichkeit:
- < 0.118ng/mL
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- 2Â[o]C to 8Â[o]C|-20Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Assay Kits: ELISAs
- Datenblatt des Herstellers:html_datasheet.php