BAX ELISA Kit
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96 Wells
£1042,00
OKCD07340-96WELLS
Über dieses Produkt
- SKU:
- OKCD07340
- Zusätzliche Namen:
- apoptosis regulator BAX;BCL2-associated X protein.
- Weitere Details:
- Accelerates programmed cell death by binding to; and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions; undergoes a conformation change that causes translocation to the mitochondrion membrane; leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3; and thereby apoptosis. BAX deficiency leads to lymphoid hyperplasia and male sterility; because of the cessation of sperm production (By similarity). Interacts (via a C-terminal 33 residues) with NOL3 (via CARD domain); inhibits BAX activation and translocation and consequently cytochrome c release from mitochondria (By similarity).
- Gendetails:
- BCL2 associated X; apoptosis regulator
- Proteindetails:
- Apoptosis regulator BAX
- Empfindlichkeit:
- < 4.6pg/mL
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- 2Â[o]C to 8Â[o]C|-20Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Assay Kits: ELISAs
- Datenblatt des Herstellers:html_datasheet.php