DNASE1 ELISA Kit
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96 Wells
£842,00
OKCD07167-96WELLS
Über dieses Produkt
- SKU:
- OKCD07167
- Zusätzliche Namen:
- AI788650;Deoxyribonuclease I;deoxyribonuclease-1;DN;DNaseI;Dnl1.
- Weitere Details:
- Serum endocuclease secreted into body fluids by a wide variety of exocrine and endocrine organs (PubMed:29191910). Expressed by non-hematopoietic tissues and preferentially cleaves protein-free DNA. Among other functions; seems to be involved in cell death by apoptosis. Binds specifically to G-actin and blocks actin polymerization (By similarity). Together with DNASE1L3; plays a key role in degrading neutrophil extracellular traps (NETs) (PubMed:29191910). NETs are mainly composed of DNA fibers and are released by neutrophils to bind pathogens during inflammation (PubMed:29191910). Degradation of intravascular NETs by DNASE1 and DNASE1L3 is required to prevent formation of clots that obstruct blood vessels and cause organ damage following inflammation (PubMed:29191910).
- Gendetails:
- deoxyribonuclease I
- Proteindetails:
- Deoxyribonuclease-1
- Empfindlichkeit:
- < 0.51ng/mL
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- 2Â[o]C to 8Â[o]C|-20Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Assay Kits: ELISAs
- Datenblatt des Herstellers:html_datasheet.php