CLCF1 Chemi-Luminescent ELISA Kit
Produktgrößen
96 Wells
£1157,00
OKCD05580-96WELLS
Über dieses Produkt
- SKU:
- OKCD05580
- Zusätzliche Namen:
- B-cell stimulating factor 3;Bsf3;cardiotrophin-like cytokine factor 1;Clc;NNT-1;novel neurotrophin-1.
- Weitere Details:
- This gene is a member of the glycoprotein (gp)130 cytokine family and encodes cardiotrophin-like cytokine factor 1 (CLCF1). CLCF1 forms a heterodimer complex with cytokine receptor-like factor 1 (CRLF1). This dimer competes with ciliary neurotrophic factor (CNTF) for binding to the ciliary neurotrophic factor receptor (CNTFR) complex; and activates the Jak-STAT signaling cascade. CLCF1 can be actively secreted from cells by forming a complex with soluble type I CRLF1 or soluble CNTFR. CLCF1 is a potent neurotrophic factor; B-cell stimulatory agent and neuroendocrine modulator of pituitary corticotroph function. Defects in CLCF1 cause cold-induced sweating syndrome 2 (CISS2). This syndrome is characterized by a profuse sweating after exposure to cold as well as congenital physical abnormalities of the head and spine. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
- Gendetails:
- cardiotrophin-like cytokine factor 1
- Proteindetails:
- Cardiotrophin-like cytokine factor 1
- Empfindlichkeit:
- < 1.18pg/mL
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- 2Â[o]C to 8Â[o]C|-20Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Assay Kits: ELISAs
- Datenblatt des Herstellers:html_datasheet.php