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Assay-Kits & ELISAs

GRIN2A ELISA Kit

Produktgrößen
96 Wells
£1096,00
OKCD04531-96WELLS
Über dieses Produkt
SKU:
OKCD04531
Zusätzliche Namen:
EPND;FESD;GluN2A;Glutamate [NMDA] receptor subunit epsilon-1;glutamate ionotropic receptor NMDA 2A;glutamate receptor ionotropic; NMDA 2A;glutamate receptor; ionotropic; N-methyl D-aspartate 2A;LKS;NMDAR2A;N-methyl D-aspartate receptor subtype 2A;N-methyl-D-aspartate receptor channel; subunit epsilon-1;N-methyl-D-aspartate receptor subunit 2A;NR2A.
Weitere Details:
Component of NMDA receptor complexes that function as heterotetrameric; ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit; glycine binding to the zeta subunit; plus membrane depolarization to eliminate channel inhibition by Mg(2+) (PubMed:8768735; PubMed:26919761; PubMed:26875626; PubMed:28105280). Sensitivity to glutamate and channel kinetics depend on the subunit composition; channels containing GRIN1 and GRIN2A have higher sensitivity to glutamate and faster kinetics than channels formed by GRIN1 and GRIN2B (PubMed:26919761; PubMed:26875626). Contributes to the slow phase of excitatory postsynaptic current; long-term synaptic potentiation; and learning (By similarity).
Gendetails:
glutamate ionotropic receptor NMDA type subunit 2A
Proteindetails:
Glutamate receptor ionotropic; NMDA 2A
Empfindlichkeit:
< 1.33ng/mL
Versandbedingungen:
Blue Ice
Lagerbedingungen:
2Â[o]C to 8Â[o]C|-20Â[o]C
Hersteller:
Aviva Systems Biology
Typ:
Assay Kits: ELISAs