Anti-MAG ELISA Kit
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96 Wells
£1070,00
OKCD04530-96WELLS
Über dieses Produkt
- SKU:
- OKCD04530
- Zusätzliche Namen:
- GMA;myelin-associated glycoprotein;sialic acid binding Ig-like lectin 4A;sialic acid-binding immunoglobulin-like lectin 4A;SIGLEC4A;SIGLEC-4A;S-MAG;SPG75.
- Weitere Details:
- Adhesion molecule that mediates interactions between myelinating cells and neurons by binding to neuronal sialic acid-containing gangliosides and to the glycoproteins RTN4R and RTN4RL2 (By similarity). Not required for initial myelination; but seems to play a role in the maintenance of normal axon myelination. Protects motoneurons against apoptosis; also after injury; protection against apoptosis is probably mediated via interaction with neuronal RTN4R and RTN4RL2. Required to prevent degeneration of myelinated axons in adults; this probably depends on binding to gangliosides on the axon cell membrane (By similarity). Negative regulator of neurite outgrowth; in dorsal root ganglion neurons the inhibition is mediated primarily via binding to neuronal RTN4R or RTN4RL2 and to a lesser degree via binding to neuronal gangliosides. In cerebellar granule cells the inhibition is mediated primarily via binding to neuronal gangliosides. In sensory neurons; inhibition of neurite extension depends only partially on RTN4R; RTN4RL2 and gangliosides. Inhibits axon longitudinal growth (By similarity). Inhibits axon outgrowth by binding to RTN4R (By similarity). Preferentially binds to alpha-2;3-linked sialic acid. Binds ganglioside Gt1b (By similarity).
- Gendetails:
- myelin associated glycoprotein
- Proteindetails:
- Myelin-associated glycoprotein
- Empfindlichkeit:
- < 0.59ng/mL
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- 2Â[o]C to 8Â[o]C|-20Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Assay Kits: ELISAs
- Datenblatt des Herstellers:html_datasheet.php