GDF5 Chemi-Luminescent ELISA Kit
Produktgrößen
96 Wells
£1070,00
OKCD03523-96WELLS
Über dieses Produkt
- SKU:
- OKCD03523
- Zusätzliche Namen:
- b;BMP-14;bone morphogenetic protein 14;bp;brp;cartilage-derived morphogenetic protein-1;CDMP-;Cdmp-1;growth/differentiation factor 5.
- Weitere Details:
- Growth factor involved in bone and cartilage formation. During cartilage development regulates differentiation of chondrogenic tissue through two pathways. Firstly; positively regulates differentiation of chondrogenic tissue through its binding of high affinity with BMPR1B and of less affinity with BMPR1A; leading to induction of SMAD1-SMAD5-SMAD8 complex phosphorylation and then SMAD protein signaling transduction (By similarity). Secondly; negatively regulates chondrogenic differentiation through its interaction with NOG (By similarity). Required to prevent excessive muscle loss upon denervation. This function requires SMAD4 and is mediated by phosphorylated SMAD1/5/8 (PubMed:24076600). Binds bacterial lipopolysaccharide (LPS) and mediates LPS-induced inflammatory response; including TNF secretion by monocytes (By similarity).
- Gendetails:
- growth differentiation factor 5
- Proteindetails:
- Growth/differentiation factor 5
- Empfindlichkeit:
- 0.156 ng/mL
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- 2Â[o]C to 8Â[o]C|-20Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Assay Kits: ELISAs
- Datenblatt des Herstellers:html_datasheet.php