CMTM6 Chemi-Luminescent ELISA Kit
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96 Wells
£1016,00
OKCD03377-96WELLS
Über dieses Produkt
- SKU:
- OKCD03377
- Zusätzliche Namen:
- chemokine-like factor super family 6;chemokine-like factor superfamily 6;chemokine-like factor superfamily member 6;CKLF-like MARVEL transmembrane domain-containing protein 6;CKLFSF6;PRO2219.
- Weitere Details:
- Master regulator of recycling and plasma membrane expression of PD-L1/CD274; an immune inhibitory ligand critical for immune tolerance to self and antitumor immunity. Associates with both constitutive and IFNG-induced PD-L1/CD274 at recycling endosomes; where it protects PD-L1/CD274 from being targeted for lysosomal degradation; likely by preventing its STUB1-mediated ubiquitination. May stabilize PD-L1/CD274 expression on antigen presenting cells and potentiates inhibitory signaling by PDCD1/CD279; its receptor on T-cells; ultimately triggering T-cell anergy.
- Gendetails:
- CKLF like MARVEL transmembrane domain containing 6
- Proteindetails:
- CKLF-like MARVEL transmembrane domain-containing protein 6
- Empfindlichkeit:
- 6.9 pg/mL
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- 2Â[o]C to 8Â[o]C|-20Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Assay Kits: ELISAs
- Datenblatt des Herstellers:html_datasheet.php